12 Worst and Deadliest Diseases in the World

Since 19th century, the science and medicine has extinguished and eradicated many diseases. And there are also many diseases which have to be suppressed. Every year, millions of people around the world die due to some deadly diseases. There are some exceptional diseases many people suffering from around the globe. Do you know the number of people died from diseases is more than those people who died in accidents? Some diseases are found frequently and some are so rare that even a team of professional doctors is not able to diagnose those diseases. Read more in the following list of 12 Worst and Deadliest Diseases in the World with their causes and symptoms.

12. Cerebrovascular Disease

Cerebrovascular DiseasePhoto credit: Wikimedia

Cerebrovascular disease is a scientific name of heart attack. This disease results a stroke when the blood flow to a part of the brain is interrupted. It could be dangerous for patients if the blood flow through brain stops even for a few seconds. High blood pressure is a common risk factor for an attack. Other causes are tension, smoking, diabetes and obesity. This disease is very common for the people at age group of 55-70.

11. SARS

SARSPhoto credit: Wikimedia

SARS or severe acute respiratory syndrome is a respiratory disease caused by the coronavirus. In 2002, SARS evolved in China and within one year it spreads in more than 37 countries all over the globe. This is a viral disease, so patients need treatment in full ventilation. As of 2014, there is no vaccine or cure that that could save human life suffering from SARS. Its virus is still active in nature and may return in future. It is considered a deadliest disease because 10% patients died during treatment.

10. Polio

Polio or poliomyelitis is an infectious disease which affects the nervous system and partially or completely paralyzes the body. The first case of polio was recognized in 1840. Till 1977, there were more than 250,000 polio infected person living in the United States. The World Health Organization estimates that there are around 20 million polio survivors worldwide. World Polio Day, 24 October was celebrated to commemorate the birth of Jonas Salk who developed a vaccine against polio. Since then, the number of cases of polio has reduced by 99%.

9. Rabies

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Rabies is a deadly disease which causes swelling of the brain. It can be transmitted through infected bats, monkeys, dogs, wolves, coyotes and mongoose. Most cases are recorded of a dog bite. According to statistics, around 50,000 people die every year due to rabies. In 1990, 54,000 people died from rabies and an estimated 26,000 died in 2010. India has the highest number of human rabies cases in the world because of street dogs. There is no healing vaccine of rabies but some vaccines are discovered to control this disease. 28th September is remembered as World Rabies Day which promotes the information about prevention and cure of the rabies.

8. Dengue

Dengue fever is also known as break-bone fever and its symptoms include pain in joints, headache and fever. Dengue virus is transmitted by Aedes mosquitoes and they usually bite during the day time. In few cases, the virus results in bleeding and low blood platelets. There is no specific vaccine for the dengue virus and treatment depends on the symptoms. It infects 50-500 million people worldwide a year and kills 25,000 people. The virus is more active in urban environment and the numbers of cases has been increased by 30 times (as of 2010).

7. Malaria

Malaria1Photo credit: wikimedia

Malaria is a mosquito infectious disease caused by protozoan parasites. Malaria is a vector mediated protozoan disease caused by female anopheles mosquito. Its symptoms include fever and headache and in extreme cases it causes coma or death. It is transmitted through the bite of an infected mosquito and most cases are recorded in tropical regions. Each year more than 500 million people get infected by the Malaria virus and it kills over one million people all over the world. No vaccine has been developed so far and prevention drugs must be taken regularly to reduce the risk of infection.

6. Tuberculosis

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Tuberculosis is one of the deadliest diseases caused by Mycobacteria Tuberculosis. It is a communicable disease as it spread through the air when an infected person cough or sneeze. Mostly it attacks the lungs but can also affect other body parts. Its symptoms include low fever, long-term cough and weight loss. It is estimated that more than one-third of world’s population have been infected with this bacteria. According to the report, it kills more than 50% infected persons. Most cases are recorded from developing countries because of poor immune system. As of 2008, there were an estimated 22 million active patient across the globe. TB can be prevented with the Bacillus-Calmette-Guerin vaccine.

5. Ebola

EbolaPhoto credit: wikimedia

Ebola virus disease is the human disease caused by the Ebola virus. Its symptoms are headache with fever, diarrhea, vomiting and dysfunction of liver and kidney. The Ebola virus was first noticed in 1976 in Sudan and more than 150,000 people were killed since 2000. The disease has a very high rate of death possibility of up to 80-90%. There is no treatment available for the virus and scientists are putting lots of effort to develop a permanent cure. This year, the virus back in human’s climate and killed over 5000 patients only in 2014 till October. The Health Ministry of Russia claims that they have developed the vaccine for Ebola virus and available for trials as soon as early 2015.

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4. Influenza

Influenza1Photo credit: wikimedia

Influenza is a communicable disease of mammals and birds, cause by RNA virus, Influenza virus. The common symptoms are fever, fatigue, cough, pain in muscle and running nose. It spreads all over the world in seasonal diseases and affects around five million people yearly. Flu is responsible for more than 400,000 deaths every year.  The unforgettable 1918 flu infected 500 million people all over the world and killed around 100 million of them. The flu virus is deactivated by sunlight and detergents. Moreover, regular hand washing can reduce the rate of infection.

3. Bubonic Plague

Bubonic plague is a zoonotic disease which can be transmitted from animals to people. Its symptoms are high fever, muscle cramps, extreme pain in muscle, skin color change and infection of the lymph glands. In the 14th century, the plague killed an estimated 50% of the European population. Bubonic plague kills two third of the infected person who don’t get treatment. Infected people should be given antibiotics within 24 hours to prevent death. Many antibiotics are available for the treatment such as streptomycin and gentamicin.

2. Cancer

Cancer virusPhoto credit: wikimedia

Cancer is one of the deadliest disease in which the cells divide and grow unruly. There are more than 200 different types of cancers. Until the cancer goes to an extreme level, it produces no symptoms. The causes of cancers are very complex and only a small part is unveiled. Many cancers can be prevented just by eating more vegetable, stop smoking and eating tobacco, maintain health and regular exercise. Only in 2007, 7.9 million people died due to Cancer. Every year, around 200,000 people lose their lives (worldwide) from cancer.


AIDS logo - Deadliest Diseases in the WorldPhoto credit: wikimedia

Also Read: Rarest Diseases in the World

Acquired Immuno Deficiency Disease or AIDS is the deadliest disease caused by HIV virus. In the initial stage, an infected person feels like flu-like illness. HIV virus shows its entire symptoms at the last stage. It is communicable disease and transmitted via contaminated blood transfusion, unprotected intercourse and mother to child during pregnancy. It was first recognized in 1981 and is responsible for 36 million deaths since its discovery. Records say that more than 35 million people are living across the globe with HIV infection. Without treatment, the infected person survives up to 9-11 years. There is no vaccine invented for the virus but antiretroviral treatment can slow the effect of the disease and increase life expectancy to a normal person’s life span.

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